The Osler Medical Journal: Topic Reviews
نویسنده
چکیده
Fulminant hepatic failure (FHF) is a true medical emergency. It is a clinical syndrome characterized by the appearance of sudden marked impairment of liver cell function with hepatic encephalopathy, resulting from acute necrosis or dysfunction of a large portion of liver parenchyma. It is uncommon, but not rare. An estimated 2000 to 2500 deaths per year in the United States are due to FHF. Even with supportive medical care, the mortality rate ranges from 50% to 90%, primarily because of associated cerebral edema, sepsis, and multiorgan failure[1,2,3].
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تاریخ انتشار 2001